I was hoping they would be able to mix the plots of Year One and The Killing Joke. It would be nice to see the Joker and Batman origins tied together. It could work by monkeying with the timelines of the stories (lots of build-up from Jack's initial attempt at crime resulting in the death of the Waynes to his ultimate descent into crime and eventual madness while Bruce's story unfolds). In fact it would play real nice if Bats' story was put in the background to an extent, allowing the focus to be on Joker. And then, when everything comes to a head in the chemical factory and you get to see how integral Batman is in Joker's origin, hopefully the poison of those last two movies would wash away.
And it'd make a nice backstory if they ever decide to do The Dark Night.
But somehow I figure none of that will come into play (I haven't gotten to read Year One yet, so I don't know what the exact dynamics are anyway).
But with Nolan at the helm it should be pretty kickin' regardless.
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Ham-fisted ham fisting.